Sildenafil is usually a strong and selective inhibitor of cGMP-unique phosphodiesterase sort 5 (PDE5), and that is responsible for degradation of cGMP while in the corpus cavernosum. The molecular structure of sildenafil is similar to that of cGMP and acts to be a competitive binding agent of PDE5 while in the corpus cavernosum, leading to more cGM

Sildenafil is in a class of medicines named phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by expanding blood circulation into the penis all through sexual stimulation. This increased blood movement may cause an erection. Sildenafil treats PAH by comforting the blood vessels from the lungs to permit blood to movement eas